Wolves face West Bromwich Albion on Saturday in what is a huge Black Country derby for both sides.
Wolves have won just one game in their last eight outings in the Premier League and are desperate to end their torrid run.
Tuesday’s defeat to Everton saw Wolves show promise but ultimately fail to produce enough clear-cut chances – which has been a recurring theme this season.
Standing in the way of three badly needed points are a West Brom side fighting for their Premier League lives under new manager Sam Allardyce, who has lost four of his five games in charge so far.
In goal Rui Patricio will retain his place for Wolves, and the 32-year-old needs a strong performance having been questioned in recent weeks.
At the back, it makes sense for Nuno to stick with a back four to try and take the game to Albion, who are by far the worst defensive side in the division with 39 goals conceded in just 17 games.
£10 million star Willy Boly (BBC Sport) is back fit again and while the temptation will be to go five at the back, maybe Nuno will deploy the Ivorian alongside captain Conor Coady at the expense of Romain Saiss, with Nelson Semedo and Rayan Ait-Nouri as the full-backs.
In midfield, Ruben Neves, Leander Dendoncker and Joao Moutinho will all probably start. Despite his advancing years, Moutinho has been a constant pick for the manager recently and his quality will be needed to unlock a potentially stubborn and Allardyce-influenced Baggies defence.
Up front, fans will hope for Pedro Neto to provide a spark as he usually does, and that Adama Traore, 24, will have recovered from his hamstring issue that ruled him out against Everton.
Patrick Cutrone has surely got to be handed a start on Saturday after returning from his loan with Fiorentina.
The Italian has had two sub appearances since coming back to Molineux, but this could be his chance, with £80,000-a-week youngster (Spotrac) Fabio Silva having unfortunately looked a little toothless – although it is very difficult for him with his price tag and lack of experience.