Wolves take on Manchester United at Old Trafford tonight, just 48 hours on from the 1-1 draw against Tottenham Hotspur.
Nuno’s side will be hoping to get back to winning ways after going two games without victory.
Standing in their way of three points is a United side who have been much improved in recent weeks under Ole Gunnar Solskjaer.
The Red Devils are unbeaten in their last eight games in the Premier League, and tonight’s clash will be tough.
Although Rui Patricio might have done better with Tanguy Ndombele’s goal on Sunday night, his position in the starting XI is not under any threat.
It is always so difficult to predict what system Nuno will go with, but against United, a back four could be the way to go.
United’s backline is the weakest aspect of their team and Wolves have to try and take the game to them.
If it is to be a back four, Nelson Semedo, Conor Coady, Romain Saiss and £36,500-a-week talent Rayan Ait-Nouri (Spotrac) is perhaps the best bet at Old Trafford – Willy Boly may be lacking a bit of match fitness, and Fernando Marcal went off injured against Spurs.
In midfield, Ruben Neves will probably get the nod, but £5 million veteran Joao Moutinho (BBC Sport) could drop out in the interest of keeping things fresh, with Owen Otasowie his replacement and Daniel Podence operating as a number 10.
On the wings, Pedro Neto and Adama Traore could be the best bets to get joy against Aaron Wan-Bissaka and Luka Shaw/Alex Telles, and Fabio Silva showed real promise against Spurs and deserves to keep his place leading the line.
With this four at the back system the signs have been there, it’s just about being more clinical. With players like Neto and Podence on song, the creation of chances shouldn’t be an issue.